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Search Results

Showing results 21 to 40 of 68.

Article

Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization

August 15, 2019
Patent

Apelin receptor (APJ) agonists and uses thereof

August 13, 2019
Article

Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as peripherally restricted inverse agonists of the CB1 receptor

July 11, 2019
Article

A patent update on cannabinoid receptor 1 antagonists (2015-2018)

April 03, 2019
Patent

Apelin receptor (APJ) agonists and uses thereof

October 16, 2018
Article

Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists

August 15, 2018
Article

Discovery of a potent, selective, and brain-penetrant small molecule that activates the orphan receptor GPR88 and reduces alcohol intake

August 09, 2018
Article

Development of a peripherally restricted aryl urea based cb1 receptor antagonist for alcoholic steatosis

August 01, 2018
Article

Blocking alcoholic steatosis in mice with a peripherally restricted purine antagonist of the type 1 cannabinoid receptor

May 24, 2018
Article

Development of a peripherally restricted cb1 receptor antagonist for alcoholic steatosis

October 01, 2017
Chapter

Metabolic profiling of CB1 neutral antagonists: (Chapter 9)

July 01, 2017
Article

Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88

March 27, 2017
Patent

Peripherally restricted diphenyl purine derivatives

October 04, 2016
Article

Peripherally selective cannabinoid 1 receptor (CB1R) agonists for the treatment of neuropathic pain

August 25, 2016
Article

Discovery of a novel small molecule agonist scaffold for the APJ receptor

August 15, 2016
Article

Pyrazole antagonists of the CB1 receptor with reduced brain penetration

March 01, 2016
Patent

Peripherally restricted diphenyl purine derivatives

November 17, 2015
Article

Regulation of the apelinergic system and its potential in cardiovascular disease: Peptides and small molecules as tools for discovery

October 22, 2015
Article

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3-and 4-methyl substituents

October 01, 2015
Patent

Pyrazole Derivatives as Cannabinoid Receptor 1 Antagonists

September 15, 2015