Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.
Kappa opioid receptor ligands
Carroll, F., Navarro, H., Brieaddy, L., Runyon, S., & Thomas, J. (2011). IPC No. U.S. Kappa opioid receptor ligands. (U.S. Patent No. 7,872,023).
Abstract
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