• Patent

Aminoanthraquinone derivatives to combat multidrug resistance

Citation

Sachs, C. W., Fine, R. L., Ballas, L. M., Carroll, R. I., & Bell, R. (1995). IPC No. U.S.Aminoanthraquinone derivatives to combat multidrug resistance (Patent No. 5436243.)

Abstract

Potentiating agents inhibit the development of multidrug resistance, reduce drug-resistance in drug-resistant tumors, or sensitize tumors to antineoplastic drugs, thereby potentiating the effect of antineoplastic agents. The potentiating agents are aminoanthraquinones, preferably 1,4-bis(N-substituted) amino anthraquinones, and pharmaceutically acceptable salts thereof.