Potentiating agents inhibit the development of multidrugresistance, reduce drug-resistance in drug-resistant tumors, orsensitize tumors to antineoplastic drugs, thereby potentiating theeffect of antineoplastic agents. The potentiating agents areaminoanthraquinones, preferably 1,4-bis(N-substituted) aminoanthraquinones, and pharmaceutically acceptable salts thereof.
Aminoanthraquinone derivatives to combat multidrug resistance
Sachs, CW., Fine, RL., Ballas, LM., Carroll, RI., & Bell, R. (1995). IPC No. U.S. Aminoanthraquinone derivatives to combat multidrug resistance. (U.S. Patent No. 5436243).
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