In the US, antibiotic-resistant (ABR) pathogens infect >2 million people and cause nearly 23,000 deaths annually. In 2013, the Centers for Disease Control and Prevention identified Clostridium difficile (C. diff), carbapenem-resistent Enterobacteriaceae (CRE), and drug-resistant Neisseria gonorrhoeae (N. gonorrhoeae) as the nation’s most urgent ABR threats. To understand the trajectory of ABR infections, we examined annual C. diff-, CRE-, and N. gonorrhoeae-related hospitalization and death rates in the US.
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