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Focus Areas

Substance Use, Gender, and Applied Research (SUGAR)

Developing and testing the efficacy, effectiveness, and impact of biobehavioral interventions for key populations of women, couples, and adolescents globally for HIV and other related health outcomes.

The Substance Use, Gender, and Applied Research (SUGAR) program develops and tests the efficacy, effectiveness, and impact of interventions for key populations of women, couples, and adolescents locally and globally for HIV and related health outcomes in community-based and real-world settings to reduce substance misuse, sexual risk behaviors, health disparities, gender-based violence, and gender inequality. Using applied research that incorporates biobehavioral approaches, SUGAR partners with community agencies, and community, peer and youth advisory boards comprising citizens, professionals, and members from the community, to address social and biobehavioral issues through a gender lens.

Areas of expertise:

  • Applied biobehavioral HIV prevention and treatment research (e.g., PrEP, ART)
  • Community-based research
  • Substance abuse interventions
  • Key populations of women, couples, and adolescents
  • Respondent-driven sampling and peer outreach workers
  • Randomized controlled trials to determine biobehavioral intervention efficacy, effectiveness, and comparative efficacy
  • Gender- and culturally appropriate mixed-methods data collection strategies
  • HIV counseling and testing, drug and pregnancy testing, and referrals to community health services
  • Implementation science to determine feasibility, acceptability, adoption and long-term sustainability in usual care settings

Dr. Wendee Wechsberg (Director, RTI Global Gender Center; Director, Substance Use, Gender, and Applied Research) with Dr. Felicia Browne (Senior Research Social Epidemiologist)

Partnerships & Affiliations

The SUGAR Program partners RTI’s scientific expertise with community agencies, and collaborative and advisory boards of citizens, professionals, and members from the community to improve the lives of people who use alcohol and other drugs. Substance abuse prevention partners include Bentech Technologies, Christiana Care, Positive Impact Health Centers, the UNC CFAR, Temple University, SisterLove, Inc., Setshaba Research Center, and the South African Medical Research Council. The SUGAR program is also affiliated with the RTI Global Gender Center, and the UNC Gillings School of Public Health, Duke University, and NC State University through adjunct positions.

Funding Resources for Global Substance Use & HIV Prevention Projects:

The SUGAR program’s projects have been funded by the Centers for Disease Control and Prevention, the UNC CFAR, and multiple institutes and centers of the U.S. National Institutes of Health (NIH). NIH funding includes the Eunice Kennedy Shriver National Institute of Child Health and Human Development,  National Institute of Mental Health, National Institute on Alcohol Abuse and Alcoholism, and the National Institute on Drug Abuse.

Learn more about how RTI is supporting global gender equality via the RTI Global Gender Center, and RTI’s HIV prevention research

Our Reach