Danni Harris

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Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects

Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?

Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations

Therapeutic and prophylactic vaccines to counteract fentanyl use disorders and toxicity

Discovery of arylsulfonamides as dual orexin receptor agonists

Development and assessment of a 3D pharmacophore for ligand recognition of BDZR/GABAA receptors initiating the anxiolytic response

Determinants of recognition of ligands binding to benzodiazepine receptor/GABA(A) receptors initiating sedation

Fluorescence anisotropy decay determinations of rapid reorientational motion: Complexities in the interpretation of bilayer acyl-chain and protein tryptophan dynamics

Substituted Tetrahydroisoquinolines as Selective Antagonists for the Orexin 1 Receptor

Benzodiazepine-induced hyperphagia: Development and assessment of a 3D pharmacophore by computational methods

Photophysics of tryptophan in bacteriophage T4 lysozymes

Determinants of the spin state of the resting state of cytochrome P450cam

Re-sensitizing multidrug resistant bacteria to antibiotics by targeting bacterial response regulators: Characterization and comparison of interactions between 2-aminoimidazoles and the response regulators bfmr fromand qseb fromspp

Inhibition of CYP2B4 by 2-ethynylnaphthalene: evidence for the co-binding of substrate and inhibitor within the active site

Prediction of regiospecific hydroxylation of camphor analogs by cytochrome P450cam

Three dimensional aspects of metabolism in human P450 systems

Metabolism of bergamottin by cytochromes P450 2B6 and 3A5

Determination of the rate of reduction of oxyferrous cytochrome P450 2B4 by 5-deazariboflavin adenine dinucleotide T491V cytochrome P450 reductase

P450 active site architecture and reversibility: Inactivation of cytochromes P450 2B4 and 2B4 T302A by tert-butyl acetylenes

Molecular dynamics simulations of phenylimidazole inhibitor complexes of cytochrome P450cam