Scott Runyon

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Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization

Apelin receptor (APJ) agonists and uses thereof

Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as peripherally restricted inverse agonists of the CB1 receptor

Formulation and characterization of conjugate vaccines to reduce opioid use disorders suitable for pharmaceutical manufacturing and clinical evaluation

Preclinical efficacy and characterization of candidate vaccines for treatment of opioid use disorders using clinically viable carrier proteins

Apelin receptor (APJ) agonists and uses thereof

Androstane and pregnane steroids with potent allosteric gaba receptor chloride ionophore modulating properties

Potent and selective tetrahydroisoquinoline kappa opioid receptor antagonists of lead compound (3 R)- N-[1 R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic)

Potent and selective tetrahydroisoquinoline kappa opioid receptor antagonists of lead compound (3r)-7-hydroxy-n-[(1s)-2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (pdtic)

Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists

Anti-Mullerian hormone as a biomarker for acute testicular degeneration caused by toxic insults to stallion testes

Development of a peripherally restricted aryl urea based cb1 receptor antagonist for alcoholic steatosis

Blocking alcoholic steatosis in mice with a peripherally restricted purine antagonist of the type 1 cannabinoid receptor

Opioid dose- and route-dependent efficacy of oxycodone and heroin vaccines in rats

Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse

Discovery of novel proline-based neuropeptide FF receptor antagonists

Development of a peripherally restricted cb1 receptor antagonist for alcoholic steatosis

Arylpiperazine Opioid Receptor Antagonists

Simple tetrahydroisoquinolines are potent and selective kappa opioid receptor antagonists

Identification of the first biased NPS receptor agonist that retains anxiolytic and memory promoting effects with reduced levels of locomotor stimulation