Second-generation antidepressants for preventing seasonal affective disorder in adults

Seasonal affective disorder (SAD) is a seasonal pattern of recurrent major depressive episodes that most commonly occurs during autumn or winter and remits in spring. The prevalence of SAD ranges from 1.5% to 9%, depending on latitude. The predictable seasonal aspect of SAD provides a promising opportunity for prevention. This review - one of four reviews on efficacy and safety of interventions to prevent SAD - focuses on second-generation antidepressants (SGAs).

Gartlehner, G., Nussbaumer, B., Gaynes, BN., Forneris, CA., Morgan, L., Kaminski-Hartenthaler, A., ... Winkler, DR. (2015). Second-generation antidepressants for preventing seasonal affective disorder in adults. Cochrane Database of Systematic Reviews, 11, CD011268. https://doi.org/10.1002/14651858.CD011268.pub2