• Patent

Hexahydroindenopyridine compounds having antispermatogenic activity

Citation

Cook, C., Lee, Y., Wani, M., Fail, P., & Jump, J. (1994). IPC No. U.S.Hexahydroindenopyridine compounds having antispermatogenic activity (Patent No. 5319084.)

Abstract

Hexahydroindenopyridine compounds having the following formula and relative stereochemistry ##STR1## where R.sup.1 is C.sub.1-6 alkyl, R.sup.2 is hydrogen or C.sub.1-6 alkyl and R.sup.3 is carboxyl or a group which is metabolized to a carboxyl group under mammalian physiological conditions exhibit potent antispermatogenic activity and are useful in a method of inhibiting spermatogenesis in mammals.