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Marie Gantz

Marie G. Gantz

Senior Research Statistician


PhD, Biostatistics, University of Kentucky
MS, Applied Statistics, George Mason University
BA, Rhetoric & Communications Studies, University of Virginia


Marie Gantz is an expert in statistics, focused on leading data coordinating centers (DCCs) for clinical studies. She is skilled in randomization schemes, power and sample size considerations, outcome selection, interim monitoring, and statistical analysis methods. She provides oversight for every aspect of DCC operations, including development of protocols, case report forms and manuals of operations, electronic data capture systems programming, study progress and safety reporting, quality assurance including centralized and on-site data monitoring, statistical analysis, dissemination of results, public data sharing, study drug and placebo manufacturing, biospecimen collection and transport, capitation payments to clinical sites, and logistics and communications coordination. She has expertise in a variety of statistical methods, including hierarchical models for multilevel and longitudinal data, and survival modeling.

Dr. Gantz joined RTI in 2004. Currently, she serves as Principal Investigator (PI) for the Data Coordinating Centers of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Pelvic Floor Disorders Network, and the National Institute of Diabetes and Digestive and Kidney Diseases-funded Fecal Incontinence Treatment multi-site clinical trial. She is Alternate PI for the DCCs of the NICHD Neonatal Research Network and associated Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterms, supported by the National Heart, Lung, and Blood Institute. In these roles, she collaborates with clinical investigators to design, implement, analyze, and publish data from randomized clinical trials and observational studies across a variety of clinical conditions impacting neonates, children, and adults. Her experience includes studies of gut microbiota, metabolites, and fungi, as well as microbiota from urinary and vaginal specimens. She studies clinical conditions including pelvic organ prolapse, fecal incontinence, urinary incontinence, extremely premature birth, and Prader-Willi syndrome.

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