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Search Results

Showing results 1 to 20 of 108.


Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization

August 15, 2019

Mapping the Kappa Opioid Receptor Using RTI's JDTic Compound

April 04, 2016

Preclinical efficacy and characterization of candidate vaccines for treatment of opioid use disorders using clinically viable carrier proteins

November 01, 2018

Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: A ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation

November 13, 2008

Apelin receptor (APJ) agonists and uses thereof

August 02, 2022

Opioid dose- and route-dependent efficacy of oxycodone and heroin vaccines in rats

May 01, 2018

Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound

June 01, 2014

A therapeutic combination of metyrapone and oxazepam increases brain levels of GABA-active neurosteroids and decreases cocaine self-administration in male rats

September 15, 2015

The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2

May 01, 2015

Ulipristal Acetate

April 11, 2016

Pyrazole agonist of the apelin receptor improves symptoms of metabolic syndrome in mice

March 25, 2021

9-(aminomethyl)-9,10-dihydroanthracene is a novel and unlikely 5-HT2A receptor antagonist

September 03, 1999

Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse

December 01, 2017

READDI Forethought uses the power of collaboration to accelerate scientific discovery

October 11, 2022

Hydrolytic instability of the important Orexin 1 receptor antagonist SB-334867: Possible confounding effects in in vivo and in vitro studies

November 01, 2012

Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl)}amino)tricyclo[,7]decane-2-carboxylic Acid (NTRC-844) as a selective antagonist for the rat neurotensin receptor type 2

September 21, 2016

Preclinical efficacy and selectivity of vaccines targeting fentanyl, alfentanil, sufentanil, and acetylfentanyl in rats

May 17, 2022

Efficacy and selectivity of monovalent and bivalent vaccination strategies to protect against exposure to carfentanil, fentanyl, and their mixtures in rats

May 13, 2022
News Release

RTI International Licenses Portfolio of Compounds to APIE Therapeutics

August 25, 2020

Geometry-affinity relationships of the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene

April 11, 2002