Kappa opioid receptor ligands

Kappa opioid receptor antagonists are provided that yieldsignificant improvements in functional binding assays to kappaopioid receptors relative to nor-BNI, and the use of theseantagonists in treatment of disease states that are ameliorated bybinding of the kappa opioid receptor such as heroin or cocaineaddictions.

Carroll, F., Thomas, J., & Mascarella, S. (2005). IPC No. U.S. Kappa opioid receptor ligands. (Patent No. 6974824).