• Patent

Kappa opioid receptor ligands


Carroll, F., Thomas, J., & Mascarella, S. (2005). IPC No. U.S.Kappa opioid receptor ligands (Patent No. 6974824.)


Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors relative to nor-BNI, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.