Kappa opioid receptor ligands
Citation
Carroll, F., Thomas, J., & Mascarella, S. (2005). IPC No. U.S.Kappa opioid receptor ligands (Patent No. 6974824.)
Abstract
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors relative to nor-BNI, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.