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James Blake RTI Expert Headshot

James Blake

Senior Research Chemist, DS Analytical Sciences


B.A., Chemistry, University of North Carolina, Wilmington


James Blake is a Technical and Administrative manager for a group of analytical chemists conducting chemistry support for the National Toxicology Program (NTP). He develops analytical methods to accurately quantitate and characterize test chemicals for toxicity testing as well as develop formulations for chemical for oral, IV, and skin administration of chemicals.

In this capacity, he supervises and allocates personnel, coordinates laboratory task schedules, and requires attendance at meetings with the Principal Investigator (PI) and the Project Officer. In addition, he performs method development for qualitative and quantitative analysis of compounds in support of NTP studies, obtains purities for compounds by analysis on gas–liquid chromatography (GLC), ultraviolet visible absorption (UV–Vis) spectrophotometer, high performance liquid chromatography (HPLC), and nuclear magnetic resonance (NMR) data interpretation. Mr. Blake structurally identifies compounds by infrared (IR) spectroscopy and interprets data with mass spectrometry (MS) and NMR analysis. He serves as Deputy PI and a Task Leader of the Formulations and Chemical Characterization Group on the National Toxicology Program (NTP). He also serves as a Study Director and Manager for commercial projects requiring analytical chemistry and involving both quantitation and qualitative analyses.

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