Conducting patient interviews within a clinical trial setting

By Dana B DiBenedetti, Tammy Michelle Brown, Carla Janine DeMuro-Mercon, Claire M Ervin, Sandy Anne Lewis, Sheri Fehnel

Qualitative data centered on patients’ experiences and perspectives typically go uncollected in clinical trial settings. Yet patients’ treatment experiences offer complementary insights and context on topics such as disease management, treatment gaps, and previous treatments outside of those gathered in traditional patient-reported outcome questionnaires. Qualitative interviews can capture patients’ perceptions of treatment needs, more fully explore meaningful changes experienced as a result of treatment, and reveal outcomes that are most important to patients. Asking patients detailed questions can provide insight into the “why” of a patient’s expressed thought or feeling. The inclusion of patient interviews within clinical trials is a relatively new and evolving field of research. This article delineates the types of data that may be collected during interviews with clinical trial participants and outlines two approaches to conducting qualitative research in the clinical trial setting, with a focus on maximizing the value of the resulting data.

Bibliography

DiBenedetti, D. B., Brown, T. M., DeMuro-Mercon, C. J., Ervin, C. M., Lewis, S. A., & Fehnel, S. (2018). Conducting patient interviews within a clinical trial setting. (RTI Press Publication No. OP-0054-1808). Research Triangle Park, NC: RTI Press. https://doi.org/10.3768/rtipress.2018.op.0054.1808

© 2019 RTI International. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors

Dana B DiBenedettiDana B. DiBenedetti, PhD, is an executive director of Patient-Centered Outcomes Assessment at RTI Health Solutions (RTI-HS).

Tammy Michelle BrownT. Michelle Brown, PhD, is a senior director of Patient-Centered Outcomes Assessment at RTI-HS.

Carla Janine DeMuro-Mercon

Claire M ErvinClaire Ervin, MPH, is a senior director of Patient-Centered Outcomes Assessment division at RTI-HS.

Sandy Anne LewisSandy Lewis, BSN, RN, is a senior director of Patient-Centered Outcomes Assessment at RTI-HS.

Sheri FehnelSheri E. Fehnel, PhD, is a vice president of Patient-Centered Outcomes Assessment at RTI-HS.

Contact RTI Press

To contact an author, request an exam or review copy, or seek permission to use copyrighted content, contact our editorial team.