Elaine Gay

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Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88

High-throughput cardiac safety evaluation and multi-parameter arrhythmia profiling of cardiomyocytes using microelectrode arrays

Diarylureas as Allosteric Modulators of the Cannabinoid CB1 Receptor: Structure-Activity Relationship Studies on 1-(4-Chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1)

Effects of methylprednisolone and 4-chloro-3-hydroxyanthranilic acid in experimental spinal cord injury in the guinea pig appear to be mediated by different and potentially complementary mechanisms

Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein

Rapid desensitization of the rat alpha7 nAChR is facilitated by the presence of a proline residue in the outer beta-sheet

Inhibition of native and recombinant nicotinic acetylcholine receptors by the myristoylated alanine-rich C kinase substrate peptide

Aromatic residues at position 55 of rat alpha7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization

Aromatic residues at position 55 of rat alpha7 nAChRs are critical for maintaining rapid desensitization

Gating of nicotinic ACh receptors; new insights into structural transitions triggered by agonist binding that induce channel opening

Gating of nicotinic ACh receptors: New insights into structural transitions triggered by agonist binding that induce channel opening

Structural determinates for apolipoproteinE-derived peptide interaction with the alpha7 nicotinic acetylcholine receptor

Structural determinates for apolipoprotein e-derived peptide interaction with the alpha7 nicotinic acetylcholine receptor

. Apolipoprotein E-derived peptides block alpha7 neuronal nicotinic ACh receptors expressed in Xenopus oocytes

Apolipoprotein e-derived peptides block alpha7 neuronal nicotinic acetylcholine receptors expressed in xenopus oocytes

Functional selectivity of D2 receptor ligands in a Chinese hamster ovary hD2L cell line: Evidence for induction of ligand-specific receptor states

8,9-Dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms

8,9-Dihydro-1,2,3,11b-Tetrahydrochromeno[4,3,2,-De]Isoquinoline (Dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms

Novel mechanisms of drug action: Functional selectivity at D2 dopamine receptors

Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology