Ann Decker

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Synthesis and pharmacological evaluation of 1-phenyl-3-thiophenylurea derivatives as cannabinoid type-1 receptor allosteric modulators

Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as peripherally restricted inverse agonists of the CB1 receptor

The dopamine, serotonin and norepinephrine releasing activities of a series of methcathinone analogs in male rat brain synaptosomes

Diarylureas containing 5-membered heterocycles as cb1 receptor allosteric modulators: Design, synthesis, and pharmacological evaluation

Comparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats

Potent and selective tetrahydroisoquinoline kappa opioid receptor antagonists of lead compound (3 R)- N-[1 R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic)

Potent and selective tetrahydroisoquinoline kappa opioid receptor antagonists of lead compound (3r)-7-hydroxy-n-[(1s)-2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (pdtic)

Development of serotonin transporter reuptake inhibition assays using JAR cells

Discovery of a potent, selective, and brain-penetrant small molecule that activates the orphan receptor GPR88 and reduces alcohol intake

Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family

Development of norepinephrine transporter reuptake inhibition assays using SK-N-BE(2)C cells

Synthesis and evaluation of orexin-1 receptor antagonists with improved solubility and CNS permeability

Discovery of novel proline-based neuropeptide FF receptor antagonists

Novel diarylurea based allosteric modulators of the cannabinoid CB1 receptor: Evaluation of importance of 6-pyrrolidinylpyridinyl substitution

Simple tetrahydroisoquinolines are potent and selective kappa opioid receptor antagonists

Phenylmorpholines and Analogues Thereof

Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88

Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists

Effect of substitution on the aniline moiety of the GPR88 agonist 2-PCCA: Synthesis, structure-activity relationships, and molecular modeling studies

Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl)}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a selective antagonist for the rat neurotensin receptor type 2