• Article

Synthesis of 9 beta-methyl-2-alkyl-7-oxo-5-arylmorphans

A convergent synthetic approach to 9 beta-methyl-2-alkyl-7-oxo-5-arylmorphans has been developed utilizing alkylation of the metalloenamine of 1,2,3,6-tetrahydro-4-aryl-1-alkylpyridine with 2-(chloromethyl)-3,5-dioxahex-1-ene (Okahara's reagent). (C) 1998 Elsevier Science Ltd. All rights reserved


Thomas, J., Zheng, XL., Brieaddy, L., Burgess, J., Mascarella, S., Fix, S., ... Carroll, F. (1998). Synthesis of 9 beta-methyl-2-alkyl-7-oxo-5-arylmorphans. Tetrahedron Letters, 39(39), 7001-7004.