Metal-catalysed hydrogen isotope exchange has been widely used in the preparation of deuterium- and tritium-labelled compounds. This review details the development and utility of homogeneous and heterogeneous rhodium and ruthenium catalysts for the preparation of deuterium- and tritium-labelled compounds by hydrogen isotope exchange methodology.
Rhodium- and ruthenium-catalysed hydrogen isotope exchange
Lockley, W. J. S., & Hesk, D. (2010). Rhodium- and ruthenium-catalysed hydrogen isotope exchange. Journal of Labelled Compounds and Radiopharmaceuticals, 53(11-12), 704-715. https://doi.org/10.1002/jlcr.1815
To contact an RTI author, request a report, or for additional information about publications by our experts, send us your request.
Multifaceted risk for non-suicidal self-injury only versus suicide attempt in a population-based cohort of adults
Development of a novel shared decision making aid for primary immunodeficiency diseases
Community overdose surveillance