Rhodium- and ruthenium-catalysed hydrogen isotope exchange

Lockley, W. J. S., & Hesk, D. (2010). Rhodium- and ruthenium-catalysed hydrogen isotope exchange. Journal of Labelled Compounds and Radiopharmaceuticals, 53(11-12), 704-715. https://doi.org/10.1002/jlcr.1815

Abstract

Metal-catalysed hydrogen isotope exchange has been widely used in the preparation of deuterium- and tritium-labelled compounds. This review details the development and utility of homogeneous and heterogeneous rhodium and ruthenium catalysts for the preparation of deuterium- and tritium-labelled compounds by hydrogen isotope exchange methodology.

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