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Celogentin mimetics as inhibitors of tubulin polymerization
Thombare, V. J., Holden, J. A., Reynolds, E. C., O'Brien-Simpson, N. M., & Hutton, C. A. (2020). Celogentin mimetics as inhibitors of tubulin polymerization. Journal of Peptide Science, 26(3), Article e3239. https://doi.org/10.1002/psc.3239
Bicyclic analogues of celogentin C have been synthesized in which the side chain-side chain cross-links are replaced by thioether bonds. Several of the simplified bicyclic peptides displayed potent inhibition of tubulin polymerization.
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