Autism Symptoms Across Adulthood in Men with Fragile X Syndrome: A Cross-Sectional Analysis
A cross-sectional analysis was used to examine age-related differences in ASD symptoms and corresponding differences in disruptive behavior and social skills in 281 adult men with fragile X syndrome. Four age groups were created: 18-21, 22-29, 30-39, and 40-49 years. The 18-21 year-old group was reported to have more impairments in verbal communication than the 22-29 year-old group and more restricted and repetitive behaviors than the 40-49 year-old group. There was not an age-group difference in the percentage of men who met criteria for an ASD diagnosis based on respondent-reported, current symptoms. There was a trend for an age-related difference in disruptive behavior. Findings add to understanding of the developmental trajectory of ASD symptoms in adulthood.
Hartley, S. L., Wheeler, A., Mailick, M. R., Kick, M., Mihaila, I., Bishop, E., & Bailey, D. (2015). Autism Symptoms Across Adulthood in Men with Fragile X Syndrome: A Cross-Sectional Analysis. Journal of Autism and Developmental Disorders, 45(11), 3668-3679. DOI: 10.1007/s10803-015-2513-7, 10.1007/s10803-015-2513-7