Data from Diabetes Study Now Available to Researchers

RESEARCH TRIANGLE PARK, N.C. — Data from a recent study of Type 1 diabetes, the Type 1 Diabetes Genetics Consortium, is now available to the research community through the NIDDK Central Repository, a resource developed by researchers at RTI International for The National Institute of Diabetes and Digestive and Kidney Diseases.

The study data are available free of charge. The biological samples are distributed through the Biosample Repository at Fisher BioServices and the Genetic Repository at Rutgers University and are available for a processing fee.

The study collected genotype data and information from more than 12,000 individuals, identified novel genetic variants associated with the risk of Type 1 diabetes, and verified some genetic variants found in previous studies.

"The release of data and biological samples from the repository provide a rich resource to the research community, especially the diabetes research domain," said Philip Cooley, an RTI fellow and the repository project director.

The available data sets include both phenotypic and genotypic data, including microsatellite marker genotyping data, a GWAS, major histocompatibility complex fine mapping data, and data about candidate genes that have been previously identified contributing to risk of type 1 diabetes.

The NIDDK Central Repository was established to increase the impact of current and previously funded NIDDK studies by making their data and biospecimens available to the scientific community. The repository enables scientists not involved in the original study to test new hypotheses without new data or biospecimen collection and provides the opportunity to pool data across several studies to increase the power of statistical analyses.

The repository currently houses more than 100 NIDDK-funded studies. From those studies, the repository offers resources for clinical, biochemical, statistical and genetic research, especially in the areas of diabetes, kidney, liver and digestive diseases.

To obtain data from the study, or any other released by NIDDK, visit www.niddkrepository.org.

Highlights

  • Data from the Type 1 Diabetes Genetics Consortium is now available through the NIDDK Central Repository
  • The study collected genotype data and information from more than 12,000 individuals
  • The data sets are available free of charge and include both phenotypic and genotypic data
  • The NIDDK Central Repository was developed by RTI International and houses data from more than 100 NIDDK-funded studies