Experts

Zach Demkovich

Research Public Health Analyst

Education

MPH, Infectious Diseases and Vaccinology, University of California Berkeley
BS, Biology, Illinois State University

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Zach Demkovich does product development and project management for new and innovative technologies with RTI International's Women's Global Health Imperative (WGHI) and in collaboration with our Global Health Technologies (GHT) and Technology Advancement & Commercialization (TAC) groups. He has several years of experience managing preclinical stages and GMP manufacturing of an implantable drug delivery system for HIV prevention. More recently, he’s been gaining experience in the IND submission process for all sorts of investigational products like vaccines, devices, biologics, and cell & gene therapies.

Mr. Demkovich’s notable publications include Predicting pharmacokinetics of a tenofovir alafenamide subcutaneous implant using physiologically based pharmacokinetic modelling and Characterization of a reservoir-style implant for sustained release of tenofovir alafenamide (TAF) for HIV pre-exposure prophylaxis (PrEP).

Publications

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Article

Comparative pharmacokinetics and local tolerance of tenofovir alafenamide (TAF) from subcutaneous implant in rabbits, dogs, and macaques

July 2022

Article

Tenofovir Alafenamide for HIV prevention: Review of the proceedings from the Gates foundation long-acting TAF product development meeting

June 2021

Article

Performance and stability of tenofovir alafenamide formulations within subcutaneous biodegradable implants for HIV Pre-Exposure Prophylaxis (PrEP)

November 2020

Article

Predicting pharmacokinetics of a tenofovir alafenamide subcutaneous implant using physiologically based pharmacokinetic modelling

August 2020

Related Capabilities

Focus Area

Public Health and Well-Being

Solution

Interventions and Prevention Programs

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