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Showing results 1 to 20 of 52.
Article
Intramolecular cyclization reactions of carbonyl derivatives of hydroxysulfones
March 01, 2002
Article
Synthesis and identification of novel 11beta-aryl-4',5'-dihydrospiro[estra-4,9-diene-17beta,4'-oxazole] analogs with dissociated antiprogesterone activities
November 01, 2007
Article
Convenient synthesis of tolcapone, a selective catechol-O-methyltransferase inhibitor
January 01, 2008
Article
New intramolecular alkylation and Michael addition reactions of hydroxysulfone derivatives–stereoselective preparation of functionalized cyclic ethers
September 01, 2000
Article
Pyrazole agonist of the apelin receptor improves symptoms of metabolic syndrome in mice
March 25, 2021
Article
Discovery and characterization of the first nonpeptide antagonists for the relaxin-3/RXFP3 system
June 09, 2022
Article
Development of 3-phenyltropane analogues with high affinity for the dopamine and serotonin transporters and low affinity for the norepinephrine transporter
December 25, 2008
Article
Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor
January 15, 2023
Article
Synthesis and monoamine transporter binding properties of 2beta-[3'-(substituted benzyl)isoxazol-5-yl]- and 2beta-[3'-methyl-4'-(substituted phenyl)isoxazol-5-yl]-3beta-(substituted phenyl)tropanes
July 15, 2008
Article
Synthesis and structure-activity relationship of 3ß-(4-alkylthio, -methylsulfinyl, and -methylsulfonylphenyl)tropane and 3ß-(4-alkylthiophenyl)nortropane derivatives for monoamine transporters
July 01, 2009
Article
Rxfp3 small molecule antagonist decreases alcohol self-administration in rats
June 01, 2022
Article
Discovery of a potent, selective, and brain-penetrant small molecule that activates the orphan receptor GPR88 and reduces alcohol intake
August 09, 2018
Article
Improved synthesis of N-desmethylcitalopram and N,N-didesmethylcitalopram
January 01, 2007
Article
Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists
January 15, 2017
Article
Synthesis and structure-activity relationship of 3beta-(4-alkylthio, -methylsulfinyl, and -methylsulfonylphenyl)tropane and 3beta-(4-alkylthiophenyl)nortropane derivatives for monoamine transporters
July 15, 2009
Article
A short and efficient synthesis of 3-{2-[2-(bromomethyl)thiazol-4-yl]ethynyl}-5-fluorobenzonitrile:: A precursor for PET radioligand [F-18]SP203
June 01, 2009
Article
Synthesis of ether-linked fluorocarbon surfactants and their aggregational properties in organic solvents
April 01, 2004
Article
Evaluation of amide bioisosteres leading to 1,2,3-triazole containing compounds as GPR88 agonists: Design, synthesis, and structure-activity relationship studies
August 26, 2021
Article
Practical synthesis of p-aminophenethylspiperone (NAPS), a high-affinity, selective D-2-dopamine receptor antagonist
January 01, 2008
Article
FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2–induced resistance
April 01, 2015