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Search Results

Showing results 1 to 20 of 52.

Article

Intramolecular cyclization reactions of carbonyl derivatives of hydroxysulfones

March 01, 2002
Article

Synthesis and identification of novel 11beta-aryl-4',5'-dihydrospiro[estra-4,9-diene-17beta,4'-oxazole] analogs with dissociated antiprogesterone activities

November 01, 2007
Article

Convenient synthesis of tolcapone, a selective catechol-O-methyltransferase inhibitor

January 01, 2008
Article

New intramolecular alkylation and Michael addition reactions of hydroxysulfone derivatives–stereoselective preparation of functionalized cyclic ethers

September 01, 2000
Article

Pyrazole agonist of the apelin receptor improves symptoms of metabolic syndrome in mice

March 25, 2021
Article

Discovery and characterization of the first nonpeptide antagonists for the relaxin-3/RXFP3 system

June 09, 2022
Article

Development of 3-phenyltropane analogues with high affinity for the dopamine and serotonin transporters and low affinity for the norepinephrine transporter

December 25, 2008
Article

Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor

January 15, 2023
Article

Synthesis and monoamine transporter binding properties of 2beta-[3'-(substituted benzyl)isoxazol-5-yl]- and 2beta-[3'-methyl-4'-(substituted phenyl)isoxazol-5-yl]-3beta-(substituted phenyl)tropanes

July 15, 2008
Article

Synthesis and structure-activity relationship of 3ß-(4-alkylthio, -methylsulfinyl, and -methylsulfonylphenyl)tropane and 3ß-(4-alkylthiophenyl)nortropane derivatives for monoamine transporters

July 01, 2009
Article

Rxfp3 small molecule antagonist decreases alcohol self-administration in rats

June 01, 2022
Article

Discovery of a potent, selective, and brain-penetrant small molecule that activates the orphan receptor GPR88 and reduces alcohol intake

August 09, 2018
Article

Improved synthesis of N-desmethylcitalopram and N,N-didesmethylcitalopram

January 01, 2007
Article

Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists

January 15, 2017
Article

Synthesis and structure-activity relationship of 3beta-(4-alkylthio, -methylsulfinyl, and -methylsulfonylphenyl)tropane and 3beta-(4-alkylthiophenyl)nortropane derivatives for monoamine transporters

July 15, 2009
Article

A short and efficient synthesis of 3-{2-[2-(bromomethyl)thiazol-4-yl]ethynyl}-5-fluorobenzonitrile:: A precursor for PET radioligand [F-18]SP203

June 01, 2009
Article

Synthesis of ether-linked fluorocarbon surfactants and their aggregational properties in organic solvents

April 01, 2004
Article

Evaluation of amide bioisosteres leading to 1,2,3-triazole containing compounds as GPR88 agonists: Design, synthesis, and structure-activity relationship studies

August 26, 2021
Article

Practical synthesis of p-aminophenethylspiperone (NAPS), a high-affinity, selective D-2-dopamine receptor antagonist

January 01, 2008
Article

FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2–induced resistance

April 01, 2015