• Article

Synthesis of Some 3H Labeled 2',3'-Dideoxynucleosides of Pharmacological Interest

[Pyrimidine‐5‐3H]2′, 3′‐dideoxycytidine and [ribose 2,3‐3H]2′, 3′‐dideoxyinosine are prepared by catalytic reduction with tritium gas. [Adenine‐8‐3H]2′3′‐dideoxyadenosine is prepared by catalytic exchange with tritium gas. [Hypoxanthine‐8‐3H]2′,3′‐dideoxyinosine is prepared by the action of adenosine deaminase on [adenine‐8‐3H]2′,3′‐dideoxy‐adenosine.

Citation

Taylor, G., & Kepler, J. (1989). Synthesis of Some 3H Labeled 2',3'-Dideoxynucleosides of Pharmacological Interest. Journal of Labelled Compounds and Radiopharmaceuticals, 27(6), 683-690. https://doi.org/10.1002/jlcr.2580270611

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