• Journal Article

Synthesis of carbon-14 labeled dibutyltin dichloride

Citation

Lewin, A., Jeffcoat, A., & Berrang, B. (2007). Synthesis of carbon-14 labeled dibutyltin dichloride. Journal of Labelled Compounds and Radiopharmaceuticals, 50(3-4), 171-175. DOI: 10.1002/jlcr.1219

Abstract

This report describes the preparation of carbon-14 labeled dibutyltin dichloride from carbon-14 labeled barium carbonate in 30% overall radiochemical yield. The key steps were (a) the preparation of carbon-14 labeled butyl bromide from carbon-14 labeled barium carbonate via carbon-14 labeled butyl mesylate, and (b) the direct preparation of tetrabutyltin by the lithium-mediated reaction of dibutyltin dichloride with carbon-14 labeled butyl bromide. Copyright © 2007 John Wiley & Sons, Ltd.