Background/Rationale: To determine the suitability of published estimates of the US cost of Alzheimer’s disease (AD) for use in cost-effectiveness models for new AD treatments. Methods: A systematic literature review of published information on direct medical, direct nonmedical, indirect, and informal care costs for different levels of disease severity. Results: Nineteen studies were included in the review. In studies presenting mean costs by disease severity, the change in different types of costs with increasing disease severity varied, depending on the data sources and characteristics of patients with AD. In studies presenting the results of regression analyses, costs were shown to be independently associated with cognition, functional status, behavioral symptoms, and dependence. Conclusions: Published US studies (1) did not include all the types of costs and AD populations, and (2) generally did not include all the measures of disease severity that are needed for cost-effectiveness models.
A review of the methods used to estimate the cost of Alzheimer’s disease in the United States
Mauskopf, J., & Mucha, L. (2011). A review of the methods used to estimate the cost of Alzheimer’s disease in the United States. American Journal of Alzheimer's Disease and other Dementias, 26(4), 298-309. https://doi.org/10.1177/1533317511407481
Abstract
Publications Info
To contact an RTI author, request a report, or for additional information about publications by our experts, send us your request.
Meet the Experts
View All ExpertsRecent Publications
Article
The daily association between affect and alcohol use: A meta-analysis of individual participant data
Article
Protection of forest ecosystems in the eastern United States from elevated atmospheric deposition of sulfur and nitrogen
Article
The use of patient experience feedback in rehabilitation quality improvement and codesign activities
Article