In reply to 'The Myth of the Future Burden of CKD in United States'
In our AJKD article, we reported estimates of the future prevalence of CKD using existing definitions of the disease.1 In their letter, Drs Delanaye, El Nahas, and Glassock state that the high prevalence of CKD in persons aged 65 and older is primarily due to aging and does not represent an added mortality risk.2 A few studies have indeed found that estimated GFR values between 45 and 59?mL/min/1.73?m2 are not associated with increased mortality.3 However, other large epidemiologic studies have found that the relative and absolute risks of mortality are higher for the elderly with estimated GFR in this range than for the elderly with greater estimated GFR levels, even after controlling for albuminuria.
Hoerger, T., Burrows, NR., & Pavkov, ME. (2015). In reply to 'The Myth of the Future Burden of CKD in United States'. American Journal of Kidney Diseases, 66(1), 172-172. https://doi.org/10.1053/j.ajkd.2015.05.003