Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test
We evaluated a commercially available immunochromatographic dipstick test to detect Trypanosoma cruzi infection in 366 human serum samples with known serological results from Argentina, Ecuador, Mexico, and Venezuela. One hundred forty-nine of 366 (40.7%) and 171/366 (46.7%) samples tested positive by dipstick and serology, respectively. Dipstick sensitivity was calculated to be 84.8% (range between countries, 77.5 to 95%), and specificity was 97.9% (95.9 to 100%).
Reithinger, R., Grijalva, M. J., Chiriboga, R. F., de Noya, B. A., Torres, J. R., Pavia-Ruz, N., ... Gürtler, R. E. (2010). Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test. Journal of Clinical Microbiology, 48(8), 3003-3007. DOI: 10.1128/JCM.02474-09