Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test
Reithinger, R., Grijalva, M. J., Chiriboga, R. F., de Noya, B. A., Torres, J. R., Pavia-Ruz, N., ... Gürtler, R. E. (2010). Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test. Journal of Clinical Microbiology, 48(8), 3003-3007. DOI: 10.1128/JCM.02474-09
We evaluated a commercially available immunochromatographic dipstick test to detect Trypanosoma cruzi infection in 366 human serum samples with known serological results from Argentina, Ecuador, Mexico, and Venezuela. One hundred forty-nine of 366 (40.7%) and 171/366 (46.7%) samples tested positive by dipstick and serology, respectively. Dipstick sensitivity was calculated to be 84.8% (range between countries, 77.5 to 95%), and specificity was 97.9% (95.9 to 100%).