Prenylation inhibitors containing dimethylcyclobutane and methods of their synthesis and use

Ken S. Rehder; BB Brown; Ken S. Rehder; J-P Strachan; JH Eaves; CT Lowden

Prenylation inhibitors containing dimethylcyclobutane and methods of their synthesis and use

Brown, BB., Rehder, K., Strachan, J-P., Eaves, JH., & Lowden, CT. (2003). Prenylation inhibitors containing dimethylcyclobutane and methods of their synthesis and use. (U.S. Patent No. 6664277). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=6664277

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Abstract

The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.