Plant Antitumor Agents. 28 Resolution of a Key Tricyclic Synthon, 5'(RS)-1,5-Dioxo- (5'-Ethyl-5'-Hydroxy-2'H, 5'H, 6'H-6-Oxopyrano)[3', 4'-f]D6,8-Tetrahydroindolizine: Total Synthesis and Antitumor Activity of 20(S)- and 20(R)-Camptothecin
Citation
Wani, M., Nicholas, A., & Wall, M. (1987). Plant Antitumor Agents. 28 Resolution of a Key Tricyclic Synthon, 5'(RS)-1,5-Dioxo- (5'-Ethyl-5'-Hydroxy-2'H, 5'H, 6'H-6-Oxopyrano)[3', 4'-f]D6,8-Tetrahydroindolizine: Total Synthesis and Antitumor Activity of 20(S)- and 20(R)-Camptothecin. Journal of Medicinal Chemistry, 30, 2317.