Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers
Citation
Lee, Y., Fang, Q., Wang, Z., Li, D., & Cook, C. (1991). IPC No. U.S.Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers (Patent No. 5064823.)
Abstract
Pentacyclic triterpenoid compounds such as .alpha. boswelic acid and its acetate, .beta.-boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are disclosed. Compositions based on the pentacyclic triterpenoid compounds which can be used to treat various cancers in mammals are also disclosed.