Pentacyclic triterpenoid compounds such as .alpha. boswelic acidand its acetate, .beta.-boswellic acid and its acetate, which havean inhibitory effect on topoisomerase I and topoisomerase II, aredisclosed. Compositions based on the pentacyclic triterpenoidcompounds which can be used to treat various cancers in mammals arealso disclosed.
Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers
Lee, Y., Fang, Q., Wang, Z., Li, D., & Cook, C. (1991). IPC No. U.S. Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers. (Patent No. 5064823).
Abstract
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