In patients with chronic constipation, TD-5108, a selective 5-HT4 agonist with high intrinsic activity, relieves straining and bloating, normalizes stool consistency and reduces laxative use
Goldberg, M. R., Li, Y-P., Mangel, A. W., Johanson, J. F., Pitzer, K., & Kitt, M. M. (2008). In patients with chronic constipation, TD-5108, a selective 5-HT4 agonist with high intrinsic activity, relieves straining and bloating, normalizes stool consistency and reduces laxative use. Gastroenterology, 134(4), A547-A547.
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