• Article

Patient-level and hospital-level determinants of quality of acute stroke care: A multilevel modeling approach

Background and Purpose—Quality of care may be influenced by patient and hospital factors. Our goal was to use multilevel modeling to identify patient-level and hospital-level determinants of the quality of acute stroke care in a stroke registry. <br><br>Methods—During 2001 to 2002, data were collected for 4897 ischemic stroke and TIA admissions at 96 hospitals from 4 prototypes of the Paul Coverdell National Acute Stroke Registry. Duration of data collection varied between prototypes (range, 2–6 months). Compliance with 8 performance measures (recombinant tissue plasminogen activator treatment, antithrombotics <24 hours, deep venous thrombosis prophylaxis, lipid testing, dysphagia screening, discharge antithrombotics, discharge anticoagulants, smoking cessation) was summarized in a composite opportunity score defined as the proportion of all needed care given. Multilevel linear regression analyses with hospital specified as a random effect were conducted. <br><br>Results—The average hospital composite score was 0.627. Hospitals accounted for a significant amount of variability (intraclass correlation=0.18). Bed size was the only significant hospital-level variable; the mean composite score was 11% lower in small hospitals (145 beds) compared with large hospitals (500 beds). Significant patient-level variables included age, race, ambulatory status documentation, and neurologist involvement. However, these factors explained <2.0% of the variability in care at the patient level. <br><br>Conclusions—Multilevel modeling of registry data can help identify the relative importance of hospital-level and patient-level factors. Hospital-level factors accounted for 18% of total variation in the quality of care. Although the majority of variability in care occurred at the patient level, the model was able to explain only a small proportion. <br><br>


Reeves, MJ., Gargano, J., Maier, KS., Broderick, JP., Frankel, M., LaBresh, K., ... Schwamm, L. (2010). Patient-level and hospital-level determinants of quality of acute stroke care: A multilevel modeling approach. Stroke, 41(12), 2924-2931. https://doi.org/10.1161/STROKEAHA.110.598664