A new prenylated flavonol from the root of Petalostemon purpureus
A new prenylated flavonol, petalopurpurenol (1), and a known dihydroflavonol, petalostemumol (2), have been isolated by DNA scission-guided fractionation of the organic portion of a 20% MeOH/CHCl3/H2O partition of a 50% MeOH/CHCl3 extract of the roots of Petalostemon purpureus. Compound 2 displayed moderate activity in DNA-scission assay. Both compounds 1 and 2 were evaluated for cytotoxicity in a panel of human cancer cell lines. The structures of petalopurpurenol (1) and petalostemumol (2) were determined by spectroscopic analysis
Huang, L., Fullas, F., McGivney, R., Brown, D., Wani, M., Wall, M., ... Kinghorn, A. D. (1996). A new prenylated flavonol from the root of Petalostemon purpureus. Journal of Natural Products, 59(3), 290-292.