Mamounas, E., Poulos, C., Goertz, H-P., González, J. M., Pugh, A., & Antao, V. (2016). Neoadjuvant Systemic Therapy for Breast Cancer: Factors Influencing Surgeons’ Referrals. Annals of Surgical Oncology, Advance Online Publication, 3510-3517. Advance online publication. https://doi.org/10.1245/s10434-016-5296-y
Surgeons' decision to refer for NST is strongly driven by surgical management goals. Anatomicopathologic factors are more influential than tumor phenotype. However, no single disease or patient factor consistently drives the decision to refer for NST. Surgeons' awareness of the association between pCR achievement and longer survival could be improved.