Microspheres Design and manufacturing
Many new candidate therapeutic agents are extremely potent and must be dispensed in a controlled and accurate fashion, preferably at the site of action. These compounds may be delivered by a number of routes of administration each offering advantages and limitations based on the application.
Burgess, D. J., & Hickey, A. (2005). Microspheres: Design and manufacturing. In D. J. Burgess (Ed.), Injectable Dispersed Systems: Formulation, Processing, and Performance (pp. 305-354). Boca Raton, FL: Taylor & Francis Group.