A new thiol blocking reagent, methylsulfonyl benzothiazole, was discovered. This reagent showed good selectivity and high reactivity for protein thiols.
Methylsulfonyl benzothiazole (MSBT)
A selective protein thiol blocking reagent
Zhang, D., Devarie-Baez, N. O., Li, Q., Lancaster, J. R., & Xian, M. (2012). Methylsulfonyl benzothiazole (MSBT): A selective protein thiol blocking reagent. Organic Letters, 14(13), 3396-9. https://doi.org/10.1021/ol301370s
Abstract
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