Longitudinal Modeling of Informatively Censored Patient-Reported Outcomes Data in Oncology

Application to a Phase Iii Clinical Trial of Non-Small Cell Lung Cancer [MEETING ABSTRACT PCN139]

Houghton, K., Boye, M., Bowman, L., Brown, J., & Stull, D. (2016). Longitudinal Modeling of Informatively Censored Patient-Reported Outcomes Data in Oncology: Application to a Phase Iii Clinical Trial of Non-Small Cell Lung Cancer [MEETING ABSTRACT PCN139]. Value in Health, 19(3), A158-AA159. https://doi.org/10.1016/j.jval.2016.03.1473

Abstract

This is the first known example that directly demonstrates how PRO response is associated with OS through use of joint latent-variable PMM. Moreover, results show that use of PMM with OS analyses provides a greater understanding of treatment effect.

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