• Journal Article

Improvements in health-related quality of life among methadone maintenance clients in Dar es Salaam, Tanzania

Citation

Ubuguyu, O., Tran, O. C., Bruce, R. D., Masao, F., Nyandindi, C., Sabuni, N., ... Lambdin, B. (2016). Improvements in health-related quality of life among methadone maintenance clients in Dar es Salaam, Tanzania. International Journal of Drug Policy, 30, 74-81. DOI: 10.1016/j.drugpo.2016.03.005

Abstract

BACKGROUND: Injection of heroin has become widespread in Dar es Salaam, Tanzania and is spreading throughout the country. To prevent potential bridging of HIV epidemics, the Tanzanian government established a methadone maintenance treatment (MMT) clinic in February 2011. We assess the effect of MMT on health-related quality of life (HRQOL) and examine factors, particularly HIV infection and methadone dose, associated with changes in HRQOL. METHODS: This study utilized routine data on clients enrolling in methadone from February 2011 to April 2012 at Muhimbili National Hospital. Change in physical (PCS) and mental health (MCS) composite scores, as measured by the SF-12 tool, were the primary outcomes. Backward stepwise linear regression, with a criterion of p