• Article

Gummiferol, a cytotoxic polyacetylene from the leaves of Adenia gummifera

A new polyacetylenic diepoxide compound, gummiferol [1] was isolated from the leaves of Adenia gummifera by KB cytotoxicity-guided fractionation. Compound 1 exhibited significant activity against the KB human cell line and a broad cytotoxic spectrum against other human cancer cell lines. The structure of 1 was established primarily on the basis of its spectral data

Citation

Fullas, F., Brown, D., Wani, M., Wall, M., Chagwedera, T. E., Farnsworth, N. R., ... Kinghorn, A. D. (1995). Gummiferol, a cytotoxic polyacetylene from the leaves of Adenia gummifera. Journal of Natural Products, 58(10), 1625-1628.