• Article

Genetic and immunological host factors associated with susceptibility to HIV-1 infection

The probability of HIV transmission depends on the interplay of many different factors related to infectiousness of the HIV-infected partner, susceptibility of the HIV-uninfected partner, and biological characteristics of HIV strains. Here, we review recent studies of host immunological and genetic factors which may affect susceptibility to HIV-1 infection. These factors are summarized in Table 1. We propose how to explore biological correlates of susceptibility to HIV-1 infection in epidemiological studies, discuss the strengths and limitations of this research, and address the implications for public health

Citation

Buchacz, K. A., Wilkinson, D. A., Krowka, J. F., Koup, R. A., & Padian, N. (1998). Genetic and immunological host factors associated with susceptibility to HIV-1 infection. AIDS, 12 Suppl A:S87-94., S87-S94.