• Journal Article

Drug and alcohol trajectories among adults with schizophrenia: Data from the CATIE study

Citation

Van Dorn, R., Desmarais, S. L., Tueller, S., Jolley, J. M., Johnson, K., & Swartz, M. S. (2013). Drug and alcohol trajectories among adults with schizophrenia: Data from the CATIE study. Schizophrenia Research, 148(1-3), 126-129. DOI: 10.1016/j.schres.2013.05.006

Abstract

OBJECTIVE: The primary aim is to describe drug and alcohol trajectories in adults with schizophrenia. METHOD: Growth mixture models were used to examine disordered and non-disordered use and abstinence in the Clinical Antipsychotic Trials of Intervention Effectiveness study. RESULTS: Five classes - always abstinent; fluctuating use, abuse, and occasional abstinence; occasional (ab)use; stopped (ab)use; abusing - fit best. Overlap exists between always abstinent drug and alcohol classes; less overlap exists across other classes. CONCLUSION: There is heterogeneity in drug and alcohol use among adults with schizophrenia. The lack of overlap between classes, save always abstinent, suggests modeling drug and alcohol use separately