Comparison of the novel direct analysis in real time time-of-flight mass spectrometry (AccuTOF-DART™) and signature analysis for the identification of constituents of refined illicit cocaine
The characterization of 25 illicit cocaine samples by a novel application of direct analysis in real time (DART) sample introduction coupled with time-of-flight mass spectrometry (TOF-MS) and cocaine signature analyses is provided. The AccuTOF-DARTTM analysis of the cocaine samples resulted in the detection of most analytes, although some compounds were not detected. This new technique is easy, rapid, requires very little sample, and can be used to screen even complex mixtures. Potential applications, including use for signature analyses of controlled substances, are discussed.