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Cognitive Behavioral Therapy for Adherence and Depression (CBT-AD) in Type 2 Diabetes

Depression is one of the most common psychological problems among individuals diabetes, and it is associated with worse treatment adherence and clinical outcomes. As part of a program of treatment research aimed at integrating interventions for depression and treatment nonadherence, five depressed patients with suboptimally controlled type 2 diabetes were treated with 10-12 sessions of individual cognitive behavioral therapy for adherence and depression (CBT-AD) in a case-series design. The intervention was delivered in a hospital setting by a collaborative team consisting of a psychologist, a nurse educator, and a dietitian. Post-treatment, all participants demonstrated a decrease in depression severity and demonstrated improvements in diabetes self-care. Four of the five demonstrated improved glycemic control. These preliminary results provide evidence for the acceptability, feasibility, and potential utility of CBT-AD for patients with type 2 diabetes and depression.


Gonzalez, J. S., Dutra, L. M., Wexler D, D. D., Cagliero, E., Delahanty, L., Soper, T. D., ... Safren, S. A. (2010). Cognitive Behavioral Therapy for Adherence and Depression (CBT-AD) in Type 2 Diabetes. Journal of Cognitive Psychotherapy: An International Quarterly, 24(4), 329-343. https://doi.org/10.1891/0889-8391.24.4.329