Cocaine receptor binding ligands
Tropane derivatives having a high binding affinity andselectivity for dopamine transporters bear, on the tropane backboneeither a carboxylic ester or isoxazole moiety, as well as asubstituted phenyl moiety. The compounds have utility both aspharmaceutical and as imaging agents, when one or more atoms areradioactive.
Kuhar, M. J., Carroll, F., Boja, J. W., Lewin, A., & Abraham, P. (2006). IPC No. U.S.Cocaine receptor binding ligands (Patent No. 7011813.)