Cocaine receptor binding ligands
Kuhar, M. J., Carroll, F., Boja, J. W., Lewin, A., & Abraham, P. (2006). IPC No. U.S.Cocaine receptor binding ligands (Patent No. 7011813.)
Tropane derivatives having a high binding affinity andselectivity for dopamine transporters bear, on the tropane backboneeither a carboxylic ester or isoxazole moiety, as well as asubstituted phenyl moiety. The compounds have utility both aspharmaceutical and as imaging agents, when one or more atoms areradioactive.