• Journal Article

Cancer incidence among an HIV-infected cohort. Pulmonary Complications of HIV Infection Study Group

Citation

Johnson, C. C., Wilcosky, T., Kvale, P., Rosen, M., Stansell, J., Glassroth, J., ... Hopewell, P. (1997). Cancer incidence among an HIV-infected cohort. Pulmonary Complications of HIV Infection Study Group. American Journal of Epidemiology, 146(6), 470-475.

Abstract

Malignancies, particularly Kaposi's sarcoma and non-Hodgkin's lymphoma (NHL), are associated with human immunodeficiency virus (HIV) infection. Cancer incidence among 1,073 asymptomatic HIV-infected individuals from the Pulmonary Complications of HIV Infection Study cohort, persons from six states followed from 1988 to 1994, was examined. Total cancer incidence was 3.99/100 person-years; for Kaposi's sarcoma, incidence was 2.64 cases/100 person-years, and for NHL, it was 1.18 cases/100 person-years. Total cancer (n = 156 cases) was higher among nonblacks than among blacks (rate ratio = 2.8, 95% confidence interval 1.3-6.1), with similar results for Kaposi's sarcoma and NHL. The rate of lung cancer (n = 5) among white, homosexual/bisexual males was 0.18 per 100 person-years, suggesting a high risk of lung cancer