Camptothecin compounds with a thioether group
Gamcsik, M. P., Adams, D. J., Colvin, O. M., Wall, M., Wani, M., Manikumar, G., & Pommier, Y. (2004). IPC No. U.S.Camptothecin compounds with a thioether group (Patent No. 6825206.)
Camptothecin compounds which are effective anti-tumor compounds are disclosed. These conjugates inhibit the enzyme topoisomerase I and enhance the stability of the topoisomerase I-DNA cleavable complex.