Camptothecin analogs as potent inhibitors of topoisomerase I
Wall, M., Wani, M., Nicholas, A., & Manikumar, G. (1993). IPC No. U.S.Camptothecin analogs as potent inhibitors of topoisomerase I (Patent No. 5244903.)
A method for synthesizing camptothecin analogs using a novel hydroxyl-containing tricyclic intermediate and the camptothecin analogs produced by the process. The camptothecin analogs are effective inhibitors of topoisomerase.