Camptothecin analogs having an E-ring ketone

Wall, M., [legal representative] Wall, MA., Wani, M., & Manikumar, G. (2006). IPC No. U.S. Camptothecin analogs having an E-ring ketone. (U.S. Patent No. 7071204). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=7071204

Abstract

Camptothecin analogs having an E-ring ketone are effective antitumor compounds. These compounds inhibit the enzyme topoisomerase Iand may alkylate DNA of the associated topoisomerase I DNAcleavable complex.

Download/Explore

Publications Info

To contact an RTI author, request a report, or for additional information about publications by our experts, send us your request.

Recent Publications

Article

"Show Me the Energy Costs"
Article

Effectiveness of interventions for the remediation of lead-contaminated soil to prevent or reduce lead exposure-A systematic review
Article

Variation in estimates of heat-related mortality reduction due to tree cover in US cities
Article

Promoting reproducibility and increased collaboration in electric sector capacity expansion models with community benchmarking and intercomparison efforts