• Journal Article

Aryloxyethylamines: Binding at alpha-7 nicotinic acetylcholine receptors

Citation

Ragab, H. M., Kim, J. S., Dukat, M., Navarro, H., & Glennon, R. A. (2006). Aryloxyethylamines: Binding at alpha-7 nicotinic acetylcholine receptors. Bioorganic and Medicinal Chemistry Letters, 16(16), 4283-4286. DOI: 10.1016/j.bmcl.2006.05.080

Abstract

Structure–affinity relationships for the binding of 3-[2-(N,N,N-trimethylammonium)ethoxy]pyridine (AXPQ) at alpha-7 nACh receptors were investigated due to its close structural similarity to a known alpha-7 antagonist.